Comparisons between validated estimated glomerular filtration rate equations and isotopic glomerular filtration rate in HIV patients

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Comparisons between validated estimated glomerular filtration rate equations and isotopic glomerular filtration rate in HIV patients.

OBJECTIVE Understanding how best to measure renal function in HIV-infected patients is critical because estimated glomerular filtration rate (eGFR) in HIV-infected patients can be affected by ethnicity and body composition. We validated the available eGFR equations and compared them to the plasma Tc-diethylenetriaminepentaacetic acid (Tc-DTPA) clearance in HIV-infected patients. DESIGN Test o...

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The recent article about estimated glomerular filtration rate (GFR) by Levey and colleagues (1) is remarkable. The authors suggest that the new equation may still have some bias and especially may have less precision in patients with GFRs greater than 60 mL/min per 1.73 m 2 . This is even more important if the GFR is greater than 90 mL/min per 1.73 m 2 . In the paper's Methods section, Levey an...

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Chronic kidney disease (CKD) is a common health problem worldwide. CKD staging or classification, together with patients’ prognosis and treatment plan depend on the patients’ kidney function which is assessed by measurement of glomerular filtration rate (GFR). Estimated GFR can be obtained using serum or plasma creatinine as a main variable in equations or formulae such as Cockcroft-Gault equat...

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The glomerular filtration rate (GFR) cannot be measured by direct means, but can be assessed by urinary clearance of exogenous filtration markers such as inulin, iohexol, or iothalamate [1,2]. However, for several reasons, direct GFR measurements are not suitable for use in routine laboratory settings. Hence, it is more appropriate to derive an estimated GFR (eGFR) from various equations. Howev...

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ژورنال

عنوان ژورنال: AIDS

سال: 2012

ISSN: 0269-9370

DOI: 10.1097/qad.0b013e328356480d